Fri Nov 08 2024

20 articles - From Friday Nov 01 2024 to Friday Nov 08 2024

parm_toc.knit

Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…


Meta-analysis

meta-analyses and systematic reviews

Inflamm Bowel Dis

The Effectiveness of Oral Vancomycin on Inflammatory Bowel Disease in Patients With Primary Sclerosing Cholangitis: A Systematic Review.

Oral vancomycin appears safe and effective to treat IBD in a subset of PSC patients. Future studies would benefit from prospective data collection incorporating standardized symptomatic, endoscopic, and histologic indices. Ultimately, a well-powered RCT is needed to better assess the effectiveness, safety, and durability of OV therapy.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Adaptive changes in multiple aspects of emotion regulation in the offspring of pregnant persons receiving a diet-and-exercise intervention relative to usual pregnancy care: A randomized controlled trial.

This intervention was associated with medium/large effect size improvements in offspring ER. Larger trials are needed to confirm the potential of these interventions on offspring neurodevelopment. Clinical trial registry NCT01689961, Sept 21, 2012.

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Adulthood dietary and lifestyle patterns and risk of breast cancer: Global Cancer Update Programme (CUP Global) systematic literature review.

Advice to adopt combined aspects of a healthy diet and lifestyle according to WCRF/AICR and ACS scores, encouraging a healthy weight, physical activity, alcohol and smoking avoidance, and a healthy diet rich in fruits, vegetables, (whole)grains and cereals and discouraging red and processed meat, can be proposed to females to lower BC risk. This review was registered at PROSPERO as ID CRD42021270129 ( on 28 August, 2021, and further updated on 4 May, 2022, in order to extend the search period.

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Blood Biomarkers of Trans-Fatty Acid Intake among Nigerian Adults in the Federal Capital Territory: A Cross-Sectional Study.

These results provide a baseline assessment of TFA exposure in Nigerian adults to evaluate implementation and effect of national regulation passed in 2023. The observed subgroup differences may help identify subpopulations for targeted interventions to reduce TFA intake.

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Human milk feeding practices and serum immune profiles of one-year-old infants in the CHILD birth cohort study.

Current HMF status and (to a lesser extent) HMF history are associated with several inflammation-associated biomarkers in one-year-old infants. These results provide new evidence that HMF impacts immune activity and development and suggest hypotheses about the underlying mechanisms. They also highlight the importance of including current HMF status in immune-system-focused infant serum proteomic studies.

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Ultra-processed food consumption is associated with the acceleration of biological aging in the Moli-sani Study.

A diet rich in UPF was associated with an acceleration of biological aging in a large sample of Italian adults. The poor nutritional composition of highly processed foods weakly accounted for this association, suggesting that biological aging could be adversely influenced by nonnutrient characteristics of these foods.

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Inflamm Bowel Dis

Assessment of Treatment Response in Known Crohn's Disease-A Prospective Blinded Study Comparing the Diagnostic Accuracy of Intestinal Ultrasound, Magnetic Resonance Enterocolonography, Panenteric Capsule Endoscopy, and Fecal Calprotectin.

IUS and FC are equally effective for determining treatment response in patients with active CD. PCE is limited by the occurrence of strictures in this group of patients.

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Comparative Effectiveness of Ozanimod and Vedolizumab as First-Line Advanced Therapies in Ulcerative Colitis: A Propensity-Matched Cohort Analysis.

Our real-world study showed that ozanimod use is associated with similar corticosteroid use but higher odds of a change in therapy compared to vedolizumab when used as first-line therapy in patients with UC. Further prospective studies are needed to understand long-term outcomes.

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The Clinical Interpretation of Cluster Trials.

However, cluster trials are logistically complex to implement and have unique vulnerabilities that must be evaluated for accurate interpretation. Here, we provide a general overview of the design and statistical issues in cluster trials to facilitate their interpretation by clinicians.

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J Crohns Colitis

Characterisation of IBD heterogeneity using serum proteomics: A multicentre study.

Our findings in serum proteins support the presence of a continuous IBD spectrum rather than a clear separation of CD and UC. Within the spectrum, disease location may reflect a more similar disease than CD vs UC, as colonic CD resembled UC more closely than ileal CD.

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Effectiveness of transitional care in Inflammatory Bowel Disease; Development, Validation, and Initial outcomes of a Transition Success Score.

The Transition Success Score serves as a quantitative tool to evaluate the effectiveness of transitional care interventions and to identify inflammatory bowel disease patients at risk of encountering challenges during the transition to adult healthcare.

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Impact of histological remission for predicting clinical relapse in Crohn's disease: a post-hoc analysis of the prospective STORI cohort.

Despite correlations with endoscopy and biomarkers, histological scores did not predict clinical relapse in CD patients in remission. Thus, these scores are not recommended for clinical practice to assess relapse risk in CD.

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Labour market participation and income in patients with IBD onset before young adulthood - the role of disease severity and mental health.

Patients with IBD more often had low LMP, but their income was not affected. The subgroup of patients with severe disease and mental health conditions had the highest risk of low LMP.

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Risankizumab Is Associated With Normalization of Biomarkers in Patients With Crohn's Disease: Results From the Phase 3 ADVANCE, MOTIVATE, and FORTIFY Studies.

Risankizumab treatment led to sustained normalization of inflammatory biomarkers with improved clinical and endoscopic results.

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Pancreatology

Rs1347093 regulates microRNA-216/-217 expression and is associated with pancreatic cancer risk.

This study may reveal the biological relevance underlying rs1347093-A allele with an increase in pancreatic cancer risk. SNP rs1347093 could be meaningful as a novel biomarker for pancreatic cancer risk.

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Timing of lumen-apposing metal stents removal in pancreatic fluid collections: Could we go beyond?

Primary aim is to evaluate the AEs rate in patients with LAMS removal 4 weeks appears to be as safe as LAMS removal within 4 weeks. LAMS ≥15 mm and Head location were associated with higher rate of AE and thus should arouse more caution.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link


Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis

Symptomatic and Sonographic Improvement of Immune Checkpoint Inhibitor Enterocolitis With Risankizumab.

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Liver Transpl

Have CFTR modulators changed the need for liver and lung transplantation among patients with cystic fibrosis? An analysis of the UNOS database.

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Reply: Does the utilization of machine perfusion require a boundary for livers donated after circulatory death?

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Letters&Replies

Letters to the editors and authors’ replies

Inflamm Bowel Dis

Reply: MIND the Gap: Psychiatric Conditions in Inflammatory Bowel Disease.

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